Journal Club is a revamped monthly feature in the Paediatric Pearls newsletter. I’m happy to receive submissions from any primary or secondary care journal club you are running as long as the paper is relevant to front line health professionals working with children. Please contact me through the contact page.
With thanks this week to Dr Saskia Wills who took us through a paper on the need (or not) for LPs in children with complex febrile seizures. Her full presentation is here.
- The definition of a febrile seizure in this paper is a seizure in a child 6 months to 5 years with a fever >38o and without an underlying CNS infection or a history of afebrile seizures
- They occur in 2-4% of children <5yrs (peak at 12-18 months)
- They are classified as complex if they last >15 minutes, have a focal onset, or there are multiple episodes within 24 hours
- They are often associated with viral infections, especially HHV6
- The risk is slightly higher in boys and those with a family history of febrile convulsion
- 1/3 of children will have another febrile seizure in the future, but very few (2.4%) go on to have epilepsy. (The risk of epilepsy, which varies with different presenting features, is discussed here)
- In a retrospective French study of otherwise well children presenting with complex febrile seizures, only 5 out of 839 (0.7%) had confirmed bacterial meningitis. All of these had had a prolonged seizure plus some ongoing abnormal neurology or sign suggestive of CNS infection. The study concluded that in children with complex febrile seizures but no other signs of CNS infection, LP usually isn’t necessary. The risk of proven CNS disease is higher in those under 1yr and with a prolonged seizure. This study didn’t look at children who had other risk factors for meningitis, such as immunodeficiency.
Paper studied: Guedj R1, Chappuy H2 et al. Do All Children Who Present With a Complex Febrile Seizure Need a Lumbar Puncture? Ann Emerg Med. 2017 Jul;70(1):52-62. PubMed Link.
With thanks to Dr Dilshad Marikar for looking at the 2016 RCPCH material on managing a child with a decreased conscious level, prompted by his being on call when a 14 year old was brought to the ED with a GCS of 3.
The RCPCH algorithm has a child between 4 weeks and 18 years old enter the Decreased Consciousness (DeCon) pathway if the AVPU is “P” or “U” or if there is a new finding of GCS ≤ 14 which seems quite a low threshold and means that we will all need to use this guideline at some point. See: https://www.rcpch.ac.uk/system/files/protected/page/RCPCH%20DeCon%20Poster%20.pdf – incorporates how to identify and manage the situation and differential diagnoses. The full guideline is available here and the recommendations summary PDF, here. Some salient points:
- Consider intubation if GCS < 8 and child not improving
- Give oxygen if O2 saturation is ≤ 95%
- Check capillary blood glucose within 15 minutes
- Don’t overlook the possibility of NAI or safeguarding issues
The Avon Longitudinal Study of Parents and Children (ALSPAC) study collected information about nappy rash using self-completed questionnaires answered by parents at the end of the first four weeks of their baby’s life. The study found that 25% of the babies had experienced napkin dermatitis.
NICE has a comprehensive clinical knowledge summary on nappy rash here. Salient points:
- Skin swabs are not recommended for the management of nappy rash as the results are difficult to interpret.
- Both Candida and bacteria (such as Staphylococcus aureus) colonize healthy skin and a skin swab may be positive when infection is not present.
- A swab should only be taken when a secondary bacterial infection is suspected, to guide choice of antibiotic
This picture and more available on the excellent Primary Care Dermatology Society website. Compare this candidiasis picture with ammoniacal dermatitis and napkin eczema.
- Consider using nappies with the greatest absorbency (for example, disposable gel matrix nappies)
- Leave nappies off for as long as is practically possible. Clean and change the child as soon as possible after wetting or soiling. Use water, or fragrance-free and alcohol-free baby wipes.
- Dry gently after cleaning — avoid vigorous rubbing.
- Bath the child daily — but avoid excessive bathing (such as more than twice a day) which may dry the skin.
- Do not use soap, bubble bath, or lotions. Advise about skin care.
- Prescribe a barrier preparation to apply thinly at each nappy change, to protect the skin. Zinc and Castor Oil ointment BP or Metanium® ointment are recommended. Alternatively, white soft paraffin BP ointment or dexpanthenol 5% ointment (Bepanthen®) could be used.
- For children over 1 month of age, consider prescribing topical hydrocortisone 0.5% or 1% cream once a day for 7 days max.
It’s dark and sun-less again in the UK and everyone’s Vitamin D levels will be at rock bottom over the next couple of months. Rickets is not rare in London and neither are consequent hypocalcaemic fits in our babies and teenagers unfortunately. Hackney CCG has an easy to follow algorithm for prevention and management of Vitamin D deficiency: you can find it here.
There’s even a table which tells you which vitamin preparations are suitable for vegetarians or vegans, which are Kosher and Halal certified and which to avoid in peanut allergy.
Raised intracranial pressure this month, nappy rash, complex febrile seizures, tingling side effects of recreational nitrous oxide use and Vitamin D – again….
Please do leave comments below.
Retinoblastoma mnemonic this month. Plus information on lower sugar content recipes for the reintroduction of cows milk into a child’s diet, labial adhesions, 6 in 1 vaccine and don’t miss infantile spasms as early treatment improves overall prognosis. Do leave comments below.
Children’s cancer information this month – prevalence and red flags, a link to the excellent immunisation resource – Oxford vaccine group – for all those questions about individual immunisations that you can’t always answer, NICE’s recent UTI update and infant dyschezia. Do leave comments below.
Local anaesthetic cream this month (why do some places not use it in the under 1’s?), a link to useful “flash card” learning in the paediatric ED from Leicester, new Movicol doses, diphtheria and the last instalment of urinalysis with bilirubin and urobilinogen. A reminder also to please discuss children with glycosuria and a high BM with a paediatrician – most children have type 1 diabetes and are at risk of DKA at diagnosis. Do leave comments below: