Tag Archives: allergy

Dr Noimark’s allergy management plans

Lee Noimark is a paediatric allergist at the Royal London Hospital.  He and his team put these allergy action plans together.  Print them out for your patients to give to nursery or school in the event of an allergic reaction.  The labels are self explanatory:

Allergy Action Plan (mild-moderate)

Allergy Action Plan (mild-moderate with asthma)

Allergy Action Plan (severe)

Allergy Action Plan (severe with asthma)

 

October 2012 ready to go!

Coins, magnets and batteries on the menu this month as well as some more cows milk protein allergy resources.  A reminder about child developmental milestones courtesy of one of our medical students and NICE on headaches.  Do leave comments!

Feeding disorders

Fussy eating is one of the most common things that parents present with to both primary and secondary care.  My colleague, Ann Duthie, has kindly allowed me to paraphrase a recent talk she gave to the department on this subject.  I hope you find the structure as sensible, helpful and reassuring as we did.

FEEDING DISORDERS IN CHILDREN encompass the behaviour of those who have difficulty consuming adequate nutrition by mouth (impaired feeding), those who eat too much and those who eat the wrong thing (pica).  We have not covered here eating disorders such as anorexia or bulimia.

Common presentations include:

  • Dysphagia
  • Food refusal
  • Self feeding inadequacy
  • Excessive meal duration
  • Choking, gagging, vomiting
  • Inappropriate mealtime behaviours
  • Food selectivity by type and texture

 

Normal feeding development is as follows:

  • Up to 6 mths – breast/bottle fed milk
  • 6-12 mths – solids introduced and increased in variety & volume.  Milk intake begins to decrease.
  • At 1 yr – teeth; family diet; ½ pt milk/day; change in attitude to food; active and wt gain slows
  • 15 mths – hold spoon, messy feeding, use feeding cup

The child moves from a state of total dependency on parents for food to one in which he/she can exert control & independence to determine what is
eaten, when and how.  Some parents struggle to adapt to this:

  • Messy
  • Feeding cues can be missed
  • Parental fear that insufficient food will be taken, child will lose weight
  • Parents own food preferences
  • Rejection of a food and assumption that child will never like it
  • Time pressures

The health professional must look for an organic cause of food refusal:

Organ system GI disorder Mechanism
Mouth Carious teeth
Structural with oral
dysphagia
Pain
Reluctance to swallow
Pharynx Tonsils
Aspiration
Pain, obstruction
Choke, gag
Oesophagus Reflux oesophagitis
Cows milk allergy
Pain, burning
Stomach Motility disorder Reduced appetite,
discomfort
Colon Constipation Pain, discomfort, reduced
appetite

Children with neurodevelopmental problems or autism may have additional factors affecting their feeding behaviours.

There are 5 key elements to the assessment:

  • How is the problem manifested?
  • Is the child suffering from any disease?
  • Have child’s growth & development been affected?
  • What is the emotional climate like during mealtimes?
  • Are there any great stress factors in the family?

 

Red flags to look out for include:

  • Swallowing difficulty with cough, choke or gag
  • Vomiting/abdominal pain/arching/grimacing/eye watering
  • Recurrent chest infections
  • Stridor on feeding
  • Snoring with sleep apnoeas
  • Constipation

The history is, as always in medicine, of paramount importance and needs to be fairly detailed:

  • Birth History
  • Previous illness (inc. h/o vomiting, respiratory symptoms) & hospitalisations
  • Developmental progress
  • Chronology of feeding problem
    – Diet since birth
  • – Changes of milk formulae
    – Introduction of solids
  • Current diet (typical day)
  • What happens at meal times?
  • Family & Social history

Height and weight must be measured and plotted on an age appropriate growth chart and corrected for prematurity if less than 2 years of age.  Refer children with red flags or significant faltering growth to secondary services.

  • Management of the well child in primary care:
  • Reduce milk intake if necessary (maximum of 500mls total in 24 hours)
  • Encourage family foods
  • Meal time management (see NHS Lothian’s dietetic advice)
  • Aim: Improve infants comfort at meal times, relieve parental fears and improve parent-infant relationship

 

The multidisciplinary approach:

  • Health Visitor – can assess child within home situation
  • Dietician
  • – Nutritional assessment and feeding advice
  • – Calorie enrichment
  • – Calorie supplementation
  • – Enteral feeds (very occasionally)
  • Speech & Language therapist
  • – Direct assessment of feeding & advice in home situation
  • – Parent-child interaction
  • – Is swallow safe?
  • – Toddler feeding groups (eg. Waltham Forest’s “Ooey Gooey” group at Wood Street)

Summary points:

  • Feeding disorders in children are common
  • Occur in healthy children but assessment should be made for organic causes
  • – GI tract problems
  • – Developmental delay
  • – Autistic spectrum disorder
  • Watch out for obligate milk drinkers
  • Meal time management is crucial
  • Involve Health Visitor

 

Further resources:

Weaning your premature baby.  Free download from Leicestershire Dietetic Service 2011

Help! My child won’t eat and My child still won’t eat.  British Dietetic Association.  Available to buy in packs from http://www.ndr-uk.org/

My Child Won’t Eat by C Gonzalez                    – these are both books and the links are to www.amazon.co.uk

New Toddler Taming by C Green

Paediatric Pearls for February 2012

Click here for this month’s PDF digest!  It ‘s quite hard providing a balance of information for GPs and ED juniors now that I am only doing the one newsletter.  I think we’ve succeeded this month with neurodevelopmental milestones in Down’s syndrome and essential tremor aimed mainly at GPs and pulled elbow, anaphylaxis and the FEAST study aimed more towards the emergency medicine practitioners.  Many thanks to my colleagues who have contributed this month.  The FEAST video makes fascinating and inspiring watching for any health professional, regardless of specialty.  Do leave comments, questions, suggestions!

NICE on anaphylaxis

With thanks to my colleague, Dr Su Li, for summarising this 2011 NICE guideline for Paediatric Pearls.

Anaphylaxis: assessment to confirm an anaphylactic episode and the decision to refer after emergency treatment for a suspected anaphylactic episode

December 2011

www.nice.org.uk/cg134

Anaphylaxis is a severe, life-threatening, generalised hypersensitivity reaction involving

  • the airway (pharyngeal or laryngeal oedema) and/or
  • breathing (bronchospasm, tachypnoea) and/or
  • circulation (hypotension, tachycardia).

 

There can often be skin and mucosal changes. Patients presenting with these signs and symptoms should be diagnosed as having ‘suspected anaphylaxis’.

Anaphylaxis may be an allergic response that is

  • immunologically IgE mediated (foods, venoms, drugs, latex) or
  • non-immunologically mediated or
  • idiopathic (significant clinical effects with no obvious cause).

 

This guideline does not make any drug recommendations. These can be found at http://www.resus.org.uk/pages/reaction.pdf.

Patient Centred Care

  • Treatment and care should take into account patient’s needs and preferences
  • Patients should have the opportunity to make informed decisions about their care and treatment, in partnership with health care professionals
  • Good communication between healthcare professionals and patients is essential
  • Families and carers should be given the information and support they need
  • Care of young people in transition between paediatric and adult services should be planned and managed according to the best practice guidance described in ‘Transition: getting it right for young people

 

Recommendations

  • Document acute clinical features of the suspected anaphylaxis
  • Record the time of onset
  • Record the circumstances immediately before the onset of symptoms to help identify possible triggers

 

  • Consider taking blood samples for mast cell tryptase if reaction is thought to be immunologically mediated or idiopathic
    • First sample as soon after emergency treatment given
    • Second sample 1-2 hours (no more than 4 hours) from onset of symptoms
    • A further sample may be required at follow up with the allergy specialist to measure baseline mast cell tryptase

 

  • Children who have had emergency treatment should be admitted to hospital under the care of the paediatric team.  The resus council suggests observing the child for a pragmatic (no evidence yet) 6 hours because of the risk of a biphasic reaction.
  • Offer the child/parents a referral to an allergy specialist (see www.bsaci.org for registered allergy clinics)
  • Offer the child/parents an adrenaline injector in the interim period whilst waiting for a specialist appointment

 

  • Before discharge, offer the child/parents
    • Information about anaphylaxis (signs, symptoms, risk of recurrence of symptoms (biphasic reaction)).  Parent information leaflet here.
    • Information about what to do if a reaction occurs (use adrenaline injector, call emergency services)
    • Demonstration on how to use an adrenaline injector see http://www.youtube.com/watch?v=pgvnt8YA7r8 for a clear American description of how to use it.
    • Advice about how to avoid potential triggers
    • Information about the need for referral and the referral process to an allergy specialist
    • Information about patient support groups

 

Research Recommendations

  • Mast cell tryptase is not always elevated in children, particularly if food is thought to be the allergen or if respiratory compromise is the main clinical feature. It is recommended that further studies be carried out to identify other potential chemical inflammatory mediators.
  • There is limited evidence on biphasic reactions. Follow up studies are recommended.
  • There are no studies on length of observation period following emergency treatment for suspected anaphylaxis
  • There is limited data on the annual incidence or anaphylactic reactions and their associated outcomes.
  • The Guideline Development Group feel that referral to specialist services and/or the provision of adrenaline injectors are likely to benefit patients who have experienced a suspected anaphylaxis as a result of decreased anxiety and ongoing support. This benefit is yet to be quantified.

January 2012 PDF ready

Do you know your valgus from your varus?  Or your myclonic epilepsy from your sleep myoclonus?  A link this month to new asthma patient information leaflets and some reminders of NICE’s “Do not do recommendations” in feverish children.  Also the BSACI egg allergy guideline.  Do leave comments on any of these topics below.

November’s Paediatric Pearls available now!

This is the first time in ages I’ve managed to get the finalised version on line in time for the end of the month!  NICE on autism this month, a bit on the use of corticosteroids in croup with help from the Cochrane Library, update on secondary prevention of meningococcal disease and a pointer to our local educational psychologist service which is hoping to make stronger links with the borough’s GPs (see also below).  Our feeding series continues with an article on colic from one of the junior paediatricians with lots of useful links and updates.

April 2011 ED version

NICE has recently reviewed its guideline on depression in children and young people – an important diagnosis to be aware of when treating children in the ED.  We have also looked at the evidence around non-sedating antihistamines and found you a “how to do it” video on pulled elbows, and indeed one on umbilical hernia repair in an adult!  Umbilical hernias are common and benign, inguinal hernias may not be.  Read all about it here!

April 2011 GP Paediatric Pearls hot off the press!

The April 2011 version is now published.   I have covered the recently reviewed NICE guideline on depression in children and young people.  We continue with the 6 week check series with some information on umbilical hernias and granulomas.  And, now that the hay fever season is upon us, we have had a look at the literature on non-sedating antihistamines.

Anti-histamines for the hayfever season!

April 2011’s editions of Paediatric Pearls are being published late because there has been a bit of pre-publication discussion about our paragraph on anti-histamines which needed checking up on!  The newsletters go out to all my colleagues for checking prior to publication and occasionally Amutha and I have to go back to the drawing board for one or two of the text boxes.  This month 2 of the text boxes have had to be re-done, the ones on cetirizine and umbilical hernias as the surgeon with an interest in paediatrics at Whipps had some suggested modifications for this latter one.  All goes to show that this site is not just a collection of my own random thoughts….  

The full abstract of the paper on cetirizine is reproduced below:

Drugs. 2004;64(5):523-61.

Cetirizine: a review of its use in allergic disorders.

Curran MP, Scott LJ, Perry CM.

 

Source

Adis International Limited, Auckland, New Zealand. demail@adis.co.nz

 

Abstract

Cetirizine is a selective, second-generation histamine H1 receptor antagonist, with a rapid onset, a long duration of activity and low potential for interaction with drugs metabolised by the hepatic cytochrome P450 system. Cetirizine was generally more effective than other H1 receptor antagonists at inhibiting histamine-induced wheal and flare responses. Cetirizine is an effective and well tolerated agent for the treatment of symptoms of seasonal allergic rhinitis (SAR), perennial allergic rhinitis (PAR) and chronic idiopathic urticaria (CIU) in adult, adolescent and paediatric patients. In adults with these allergic disorders, cetirizine was as effective as conventional dosages of ebastine (SAR, PAR, CIU), fexofenadine (SAR), loratadine (SAR, CIU) or mizolastine (SAR). This agent was significantly more effective, and with a more rapid onset of action, than loratadine in 2-day studies in environmental exposure units (SAR). In paediatric patients, cetirizine was as at least as effective as chlorphenamine (chlorpheniramine) [SAR], loratadine (SAR, PAR) and oxatomide (CIU) in the short term, and more effective than oxatomide and ketotifen (PAR) in the long term. Cetirizine was effective in reducing symptoms of allergic asthma in adults and reduced the relative risk of developing asthma in infants with atopic dermatitis sensitised to grass pollen or house dust mite allergens. It had a corticosteroid-sparing effect in infants with severe atopic dermatitis and was effective in ameliorating reactions to mosquito bites in adults. Cetirizine was well tolerated in adults, adolescents and paediatric patients with allergic disorders. In adult, adolescent and paediatric patients aged 2-11 years, the incidence of somnolence with cetirizine was dose related and was generally similar to that with other second-generation H1 receptor antagonists. Although, its sedative effect was greater than that of fexofenadine in some clinical trials and that of loratadine or fexofenadine in a postmarketing surveillance study. In infants aged 6-24 months, the tolerability profile of cetirizine was similar to that of placebo. Cetirizine did not have any adverse effects on cognitive function in adults, or cognitive function, behaviour or achievement of psychomotor milestones in paediatric patients. Cetirizine was not associated with cardiotoxicity. CONCLUSION: Cetirizine is well established in the treatment of symptoms of SAR, PAR or CIU. It demonstrated a corticosteroid-sparing effect and reduced the relative risk of developing asthma in sensitised infants with atopic dermatitis. Cetirizine was effective in the treatment of allergic cough and mosquito bites; however, its precise role in these indications has yet to be clearly established. On the basis of its favourable efficacy and tolerability profile and rapid onset of action, cetirizine provides an important option for the treatment of a wide range of allergic disorders.